The Major Histocompatibility Complex (MHC - HLA) in Medicine - A Personal Recollection

The Major Histocompatibility Complex (MHC/ HLA) in Medicine: A Personal Recollection



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English | 2024 | ISBN: 3031598652 | 119 Pages | PDF EPUB (True) | 25 MB

The reader will learn about the molecular structure of the encoded molecules and different aspects of their role in medicine, including organ transplantation, their link to autoimmune diseases, cancer immunity, resistance to infectious diseases, and other related scientific areas, such as population genetics. In particular, the book focusses on the impact of MHC/HLA altered expression in tumours and their relevance in cancer immune escape and immunotherapy. It contains a large number of original figures and photographs of pioneers in the field, who made seminal contributions. Each chapter is supported by relevant key publications and enriched with a personal account of the early research that has contributed to our current understanding of the role of the major histocompatibility complex.

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