Vaccine Analysis: Strategies, Principles, and Control [2015] [PDF]

Title: Vaccine Analysis: Strategies, Principles, and Control
Author: Brian K. Nunnally, Vincent E. Turula, Robert D. Sitrin
Format: PDF
Hardcover: 665 pages
Publisher: Springer; 2015 edition (November 28, 2014)
Language: English
ISBN: 978-3662450239


This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities.

Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.